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As healthcare costs continue to rise, accurate cost-effectiveness estimates are crucial. However, estimating the costs and outcomes of different interventions is complicated by uncertainty. In model-based health economic evaluations (HEEs), uncertainty can arise from limited data, methodological limitations, and variability in clinical outcomes. A recent review identified 80 methods for identifying, analyzing, and communicating uncertainty in HEEs. Quantifying uncertainty wherever possible is crucial to ensure accurate and unbiased cost-effectiveness estimates, ultimately leading to optimal allocation of healthcare resources

A study on medicine shortages in the Netherlands found that disease and costs were the two most affected elements, with 30% and 20% of shortages rated high on these elements, respectively. The study used a framework of economic, clinical, and patient outcomes to assess the impact of medicine shortages on patients. Direct impact, represented by alternative product and disease, was rated high for 30% of the shortages, while indirect impact, represented by costs, susceptibility, and number of patients, was rated […]

Congratulations on the launch of the Gulf Health Economics Association! Their extraordinary initiative to bring together Health Economics experts in the Gulf Region under one entity is truly inspiring. Wishing you continued success in your future endeavors.

In surveys of ISPOR members, drug pricing was revealed to be a major concern, and one of the top 10 health economics and outcomes research issues influencing the availability of innovative treatments and healthcare decisions. Despite the fascinating ways that different research studies proposed to understand the puzzle of drug pricing, it is evident that drug prices must factor in the research uncertainties and other costs in addition to the cost of clinical trials and production and should be set […]

ISPOR HEOR held a Theater focusing on discussions from the ISPOR HTA Roundtable – Middle East and Africa. Presentations were provided by the World Health Organization, Rwanda School of Public Health, Ministry of Health of Tanzania, and Unified Procurement Authority of Egypt.

Globally, WhatsApp Messenger has emerged as one of the world’s fastest-growing MIM applications. It has particularly high penetration rates in India, Indonesia, Malaysia, Brazil and South Africa. The sub-Saharan African region is characterized by mixed migration flows and multiple health challenges, due to the inequalities experienced in access to healthcare disproportionately affect many groups including migrants and mobile populations. Given the existing structural factors impeding access to healthcare, coupled with high rates of mobile telephone use across the sub-Saharan African […]

Over the last year, we’ve made great progress towards this goal. In June 2022, NICE published our real-world evidence framework. The EMA and the European Medicines Regulatory Network recently established the Data Analysis and Real World Interrogation Network (DARWIN EU®). Using the OMOP CDM, DARWIN EU® delivers real-world evidence from across Europe on diseases, populations and the use and performance of medicines. This enables EMA and other organisations in the European medicines regulatory network to use this data whenever needed […]

After seven years of estrangement, the two countries finally decided this week to repair ties and reopen embassies. The two countries, and the rest of the Middle Eastern area, might reap significant benefits from this arrangement. The Chinese government acted as a mediator between Iran and Saudi Arabia this week, and the two countries agreed to reopen embassies and resume diplomatic relations seven years after they were closed. With the restoration of diplomatic ties, there is hope that the two […]

Introduction In public health, efficient management of Essential Medicines and Health Supplies (EMHS) is crucial. In Uganda, EMHS redistribution is a vital process that ensures healthcare facilities are equipped to serve their communities effectively.  Execution of the EMHS redistribution guidelines was lacking in public health facilities in Uganda. Just one third (33%) of the health facilities conformed with the EMHS redistribution guidelines. Understanding EMHS Redistribution EMHS redistribution involves transferring unused, non-expired health commodities from overstocked facilities to those in dire […]

Introduction The repatriation of paediatric stem cell transplants to Ireland stands as a promise for families affected by rare inherited conditions. This initiative promises to alleviate the emotional and financial strain of seeking treatment abroad, while potentially reducing healthcare expenditures. Understanding Stem Cell Transplants Stem cell transplants, particularly allogeneic haematopoietic stem cell transplants (HSCT), are life-saving procedures for children with rare conditions such as metabolic errors and haemoglobinopathies. Currently, these services are sought in the UK, under the HSE’s Treatment […]

Introduction: A transformative innovation in paediatric cardiac care is making waves: the Autus Valve. This pioneering paediatric pulmonary valve replacement promises to significantly reduce the need for invasive surgeries in children with congenital heart conditions. The Autus Valve: A Leap Forward in Pediatric Cardiology The Autus Valve stands as a glimmer of hope for approximately 110,000 children in the U.S. suffering from congenital pulmonary valve disease. Traditional prosthetic valves, unsuitable for growing bodies, necessitate multiple surgeries throughout childhood. The Autus […]

Abu Dhabi wrapped up the activities of “DoH Innovation Week 2023”, which included the announcement of the winners of the Healthcare Research and Innovation Grant and a series of panel discussions that tapped into several areas of innovation, such as, supporting entrepreneurs, design thinking, Artificial Intelligence (AI), and the National Innovation Strategy. This comes as part of DoH’s efforts to cement Abu Dhabi’s position as a leading destination for innovation in healthcare and a hub life sciences.

Abu Dhabi (DoH), is hosting “DoH Innovation Week 2023”. The four-day event will exhibit six start-ups representing the Abu Dhabi healthcare ecosystem

Introduction: New cancer therapies, such as pembrolizumab, come with high costs, presenting a unique challenge for resource allocation decisions across nations and healthcare systems. Developed countries with national universal health insurance coverage have established different methods. Time to Reimbursement of Pembrolizumab and other oncology treatment are of utmost importance for high level of care. These methods orderly and transparently assess new technologies before adding them to their list of reimbursed services. This process, known as the “fourth hurdle”, is a […]

Introduction: There is an ongoing and unrelenting effort to find better treatments for breast cancer, which is a major health concern worldwide. One promising development in this respect is the use of gene expression profiling (GEP) tests. These tests, performed on tumour samples from early-stage breast cancer patients, can help determine the potential benefits of chemotherapy post-surgery. Gene Expression Profiling Tests in Breast Cancer: The Health Information and Quality Authority (HIQA) recently published a rapid health technology assessment (HTA) on […]

Are you faced with health policy changes or looming systemic transformation? Simulation methods used in health policy and systems research (HPSR) can influence health policy making. Here is a study that illustrates how HPSR shaped universal health coverage. Health systems simulation helps prepare for uncertainty in health care systems.