
Are you faced with health policy changes or looming systemic transformation? Simulation methods used in health policy and systems research (HPSR) can influence health policy making. Here is a study that illustrates how HPSR shaped universal health coverage. Health systems simulation helps prepare for uncertainty in health care systems.
Recent Posts

Advancements in Factor XIa Inhibition Stroke Prevention Through Asundexian
The European Medicines Agency has accepted Bayer’s marketing authorization application for asundexian, marking a major advance in Factor XIa Inhibition Stroke prevention. This oral agent selectively interrupts a key step in the coagulation cascade to reduce recurrent ischemic stroke risk in adult...

Tovorafenib Clinical Assessment Outcomes and Methodological Challenges
The Tovorafenib clinical assessment conducted under the EU Joint Clinical Assessment process has exposed critical shortcomings in the evidence base for treating BRAF-altered pediatric low-grade glioma. Despite the therapy’s potential, reviewers concluded that robust comparative data is absent for...

Pioneering MDD Treatment Modeling for Optimal Care Pathways
MDD treatment modeling demonstrates that sequenced interventions for major depressive disorder consistently deliver superior quality-adjusted life years and net monetary benefits compared with no active treatment. All examined pathways outperformed inaction, with an SSRI-first sequence followed b...