Economic Impact of Industry Clinical Trials in Europe

By João L. Carapinha

February 24, 2026

Industry clinical trials in are a vital engine of medical innovation and economic growth, with the European Economic Area (EEA) generating €35.7 billion in Gross Value Added (GVA) in 2025 from these activities. This includes €21.7 billion from direct, indirect, and induced effects, €3.6 billion f...
Merck Portfolio Optimization: Strategic Reorganization for Enhanced Commercial Execution
Merck's portfolio optimization strategy includes reorganizing its Human Health division into two focused business units—Oncology and Specialty, Pharma & Infectious Diseases—to sharpen commercial execution across its growing pipeline. This
Economic Burden NSCLC: A Systematic Review of Healthcare Costs and Resource Utilization
A recently published systematic literature review synthesizes evidence from 50 publications across 43 studies on the economic burden NSCLC in locally advanced (stage IIIB/C) and metastatic (stage IV) non-small cell lung cancer, highlighting high healthcare resource utilization (HCRU) rates includ...
Enhancing Systematic Reviews: AI Literature Review Integration for Efficiency and Rigor

By João L. Carapinha

February 23, 2026

AI Literature Review Integration is transforming systematic literature reviews (SLRs), as outlined in this preprint. It provides methodological guidance for incorporating artificial intelligence (AI) into SLRs with a human-in-the-loop approa...
Administrative Court Error Complicates Infarmed Vaccine Data Transparency
Court Clerical Error Threatens Infarmed Vaccine Data Transparency Infarmed vaccine data transparency hangs in the balance due to a clerical error by the Lisbon Administrative Court's secretariat, which sent a January...
EMA Executive Director Recruitment: Leading the Future of Medicines Regulation
The EMA Executive Director Recruitment procedure has opened, a pivotal role overseeing operations like medicine authorizations, safety monitoring, and EU-wide public health responses. This vacancy, with reference COM/2026/20118, reports to the EMA Management Board, managing a 2025 budget of about...
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Economic Impact of Industry Clinical Trials in Europe

By João L. Carapinha

February 24, 2026

Industry clinical trials in are a vital engine of medical innovation and economic growth, with the European Economic Area (EEA) generating €35.7 billion in Gross Value Added (GVA) in 2025 from these activities. This includes €21.7 billion from direct, indirect, and induced effects, €3.6 billion f...

Latest

Merck Portfolio Optimization: Strategic Reorganization for Enhanced Commercial Execution
Merck's portfolio optimization strategy includes reorganizing its Human Health division into two focused business units—Oncology and Specialty, Pharma & Infectious Diseases—to sharpen commercial execution across its growing pipeline. This

Latest

Economic Burden NSCLC: A Systematic Review of Healthcare Costs and Resource Utilization
A recently published systematic literature review synthesizes evidence from 50 publications across 43 studies on the economic burden NSCLC in locally advanced (stage IIIB/C) and metastatic (stage IV) non-small cell lung cancer, highlighting high healthcare resource utilization (HCRU) rates includ...

Latest

Enhancing Systematic Reviews: AI Literature Review Integration for Efficiency and Rigor

By João L. Carapinha

February 23, 2026

AI Literature Review Integration is transforming systematic literature reviews (SLRs), as outlined in this preprint. It provides methodological guidance for incorporating artificial intelligence (AI) into SLRs with a human-in-the-loop approa...

Global Updates

Merck Portfolio Optimization: Strategic Reorganization for Enhanced Commercial Execution

By HEOR Staff Writer

February 24, 2026

Merck's portfolio optimization strategy includes reorganizing its Human Health division into two focused business units—Oncology and Specialty, Pharma & Infectious Diseases—to sharpen commercial execution across its growing pipeline. This

Global Updates

Economic Burden NSCLC: A Systematic Review of Healthcare Costs and Resource Utilization
A recently published systematic literature review synthesizes evidence from 50 publications across 43 studies on the economic burden NSCLC in locally advanced (stage IIIB/C) and metastatic (stage IV) non-small cell lung cancer, highlighting high healthcare resource utilization (HCRU) rates includ...

Global Updates

NICE Updates Type 2 Diabetes Guidelines: Emphasizing Cardiorenal Protection with SGLT2 Inhibitors

By João L. Carapinha

February 19, 2026

Type 2 Diabetes Guidelines Reshape Initial Treatment The latest Type 2 Diabetes Guidelines from NICE (National Institute for Health and Care Excellence), published on 18 February 2026 as an update to guideline NG28 ("Type 2 diabe...

Global Updates

Exploring MFN Policy Effectiveness in Drug Pricing and Innovation
MFN Policy Effectiveness in Countering Freeloading Claims The MFN policy effectiveness is evident in the coalition letter dated February 12, 2026, which opposes codifying Most-Favored-Nation (MFN) prescription drug pricing b...

Europe

Economic Impact of Industry Clinical Trials in Europe

By João L. Carapinha

February 24, 2026

Industry clinical trials in are a vital engine of medical innovation and economic growth, with the European Economic Area (EEA) generating €35.7 billion in Gross Value Added (GVA) in 2025 from these activities. This includes €21.7 billion from direct, indirect, and induced effects, €3.6 billion f...
Economic Burden NSCLC: A Systematic Review of Healthcare Costs and Resource Utilization
A recently published systematic literature review synthesizes evidence from 50 publications across 43 studies on the economic burden NSCLC in locally advanced (stage IIIB/C) and metastatic (stage IV) non-small cell lung cancer, highlighting high healthcare resource utilization (HCRU) rates includ...
Enhancing Systematic Reviews: AI Literature Review Integration for Efficiency and Rigor

By João L. Carapinha

February 23, 2026

AI Literature Review Integration is transforming systematic literature reviews (SLRs), as outlined in this preprint. It provides methodological guidance for incorporating artificial intelligence (AI) into SLRs with a human-in-the-loop approa...
Administrative Court Error Complicates Infarmed Vaccine Data Transparency
Court Clerical Error Threatens Infarmed Vaccine Data Transparency Infarmed vaccine data transparency hangs in the balance due to a clerical error by the Lisbon Administrative Court's secretariat, which sent a January...

North America

Merck Portfolio Optimization: Strategic Reorganization for Enhanced Commercial Execution

By HEOR Staff Writer

February 24, 2026

Merck's portfolio optimization strategy includes reorganizing its Human Health division into two focused business units—Oncology and Specialty, Pharma & Infectious Diseases—to sharpen commercial execution across its growing pipeline. This
Exploring MFN Policy Effectiveness in Drug Pricing and Innovation

By João L. Carapinha

February 19, 2026

MFN Policy Effectiveness in Countering Freeloading Claims The MFN policy effectiveness is evident in the coalition letter dated February 12, 2026, which opposes codifying Most-Favored-Nation (MFN) prescription drug pricing b...
Genotype ECG Prediction

By João L. Carapinha

February 17, 2026

Bridging Genotype ECG Prediction to Enhanced Cardiovascular Risk Assessment Genotype ECG prediction advancements, exemplified by the CapECG model, enable direct mapping of genetic data to electrocardiogram ...
Transformative PBM Reform Legislation Signed into Law

By João L. Carapinha

February 16, 2026

PBM Reform Legislation Signed into Law President Trump signed a comprehensive spending bill incorporating landmark PBM reform legislation, ending a partial government shutdown while targeting pharmacy benefit managers (PBMs) with transformativ...

Sub-Saharan Africa

Pharmaceutical Tender Investigation Sparks Regulatory Scrutiny in South Africa

By João L. Carapinha

February 12, 2026

Pharmaceutical Tender Investigation Targets Ascendis, Pharma Q, and Sonke The Competition Commission of South Africa has launched a pharmaceutical tender investigation into manufacturers Ascendis, Pharma Q, and...
South Africa Health Reform: Navigating Innovations and Challenges for 2026

By João L. Carapinha

February 10, 2026

South Africa Health Reform: Contrasts in 2026 Public Health Agenda South Africa health reform defines the 2026 public health landscape as a mix of breakthroughs like HIV prevention injections and AI-driven TB diagnos...
Enhancing Patient Safety in Africa’s Healthcare Transformation

By HEOR Staff Writer

February 2, 2026

Prioritizing Patient Safety Africa in 2026 Trends Patient safety Africa stands at the forefront as regulatory bodies drive healthcare self-reliance amid global shifts. A recent article (linked below) outlines five pivotal trends pro...
Navigating Economic Resilience Through Life Sciences Investment

By João L. Carapinha

January 20, 2026

Navigating a Leaderless Global Economy Through Life Sciences Investment In an era of deepening geopolitical fragmentation, often termed the G-Zero world, global governments are urged to prioritize bold life sci...