
EloraTZP Phase 2b Trial Beats Tirzepatide on Weight and A1C
A once-weekly selective amylin agonist added to tirzepatide cut 23.3% of body weight in 367 adults with obesity and type 2 diabetes, against 14.8% for tirzepatide 15 mg alone. Lilly plans Phase 3 of a co-formulated EloraTZP by the end of 2026. Discontinuation rates that reach 27% in the highest-dose arm will be the detail payers study first.
#SyenzaNews #obesity #type2diabetes #MarketAccess
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Bihormonal artificial pancreas reimbursement denied in the Netherlands
Zorginstituut Nederland has ruled that the Inreda AP stays out of the Dutch basic package. The DARE trial found no clinically relevant gain in glucose control or quality of life, serious adverse events were about three times more common, and half of the patients stopped using the device. #SyenzaNews #MedTech #MarketAccess #HealthEconomics

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Lilly Change the Course for Diabetes and Obesity in LMICs
Eli Lilly and Company has set a parity target for its diabetes and obesity medicines: treat as many people in low- and middle-income countries as in high-income countries by 2040. The commitment carries no price mechanism, so progress will be judged against Lilly’s own annual Sustainability Report. #SyenzaNews #globalhealth #pharmaceuticals #MarketAccess

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Drug prices and workforce shortages: what journalists should ask
A National Press Foundation briefing on drug prices and workforce shortages: separate list price from net price, ask which goal a policy serves, and check whether more clinicians really mean more appointments. #SyenzaNews #HealthEconomics #MarketAccess

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Germany Drug Pricing Policies Draw US Section 301 Scrutiny
Germany drug pricing policies are now the subject of a US Section 301 investigation. AbbVie’s chief counsel, Perry Siatis, has filed written evidence and testified that government price setting, mandatory rebates and reimbursement restrictions undercut the incentives that fund new medicines. He also cites a German-French working group on keeping innovative medicines available. #SyenzaNews #MarketAccess #DrugPricing #HEOR

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AI preoperative communication cuts anxiety and surgeon workload in prostate cancer
A randomized trial in 268 men awaiting radical prostatectomy found AI preoperative communication cut GAD-7 anxiety scores and nearly halved surgeon consultation time. The AI answered 2,847 of 3,507 patient questions. #SyenzaAI #SyenzaNews #MarketAccess #ProstateCancer #AIinHealthcare

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Mounjaro Portugal sales top €1 million in a day as doctors seek prescribing data
Mounjaro passed €1 million in pharmacy sales in a single day in Portugal, on more than 3,000 packs, and the Ordem dos Médicos has asked Infarmed for prescription data. Here is what the numbers show on access, reimbursement and supply. #SyenzaNews #GLP1 #MarketAccess

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The economic burden of obesity in Europe: up to 1.4% of GDP
New OHE research puts the economic burden of obesity in eight European countries at 0.7% to 1.4% of GDP. Germany carries the largest bill at EUR 55.2bn; the UK carries the largest productivity share at 58%. #SyenzaAI #SyenzaNews #MarketAccess #HealthEconomics #Obesity

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AI Governance in HTA: Ethics, Autonomy and Accountability
Syenza’s webinar on AI governance in HTA drew 71% of participants who had not yet used AI in their work. The session covered the paper’s governance checklist, the in-house Navigator tool, and a live rapid HTA of rituximab in lupus. #SyenzaNews #HTA #AIinHealth #MarketAccess

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Minimal Stimulation IVF Is Cheaper Per Cycle, but the Savings Case Is Unsettled
Minimal stimulation IVF lowers the cost of a cycle. A health economist and a US patient advocate told an IFFS webinar that the savings case, and the bill patients carry, are both unsettled. #SyenzaNews #IVF #MarketAccess #HealthEconomics

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Sweden Reports Rise in Semaglutide Adverse Reactions
Sweden’s pharmaceutical injury insurance logged 33 semaglutide adverse reactions claims in the first eight months of 2026, up from 13 in all of 2025. More prescribing and more awareness explain the rise better than any new risk.
#SyenzaNews #pharmaceuticals #drugsafety #regulatoryaffairs
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