Long-Term HPV Vaccine Effectiveness: Sustained Protection Against Cervical Disease

By João L. Carapinha

March 19, 2026

HPV vaccine effectiveness is demonstrated in new clinical and real-world data from Merck, showcasing the sustained protection of GARDASIL®9 (9-valent Human Papillomavirus [HPV] vaccine) and GARDASIL® (4-valent HPV vaccine) against HPV-related cancers and diseases. Key findings include vaccine eff...
TAVI Reimbursement Expansion for Low- and Intermediate-Risk Patients: A New Era in Cardiovascular...
The TAVI reimbursement expansion announced by Zorginstituut Nederland on March 10, 2026, includes transcatheter aortic valve implantation (TAVI) in...
PRIME Scheme Evaluation: Insights from Enhanced Development Tools Pilot
The PRIME Scheme Evaluation of the European Medicines Agency’s (EMA) PRIority Medicines (PRIME), launched in 2016, confirms early and enhanced regulatory support accelerates medicines for unmet needs. A two-year pilot (April 2023–March 2025) tested three new features—regulatory roadmap and produc...
EU Approves Imfinzi Gastric Cancer Treatment as Perioperative Immunotherapy

By João L. Carapinha

March 17, 2026

Imfinzi gastric cancer treatment has received European Commission approval for adults with resectable, early-stage and locally advanced (Stages II, III, IVA) gastric and gastroesophageal junction (GEJ) cancers. AstraZeneca’s Imfinzi (durvalumab), a PD-L1 inhibitor, combined with FLOT chemotherapy...
Europe Life Sciences Competitiveness: Addressing Decline and Unlocking Potential
Europe life sciences competitiveness is under pressure, as detailed in the EFPIA report "Asses...
Bridging Analyses: The Role of Cost Per Event Avoided in Evaluating GLP-1 Agonists
This editorial by Petrou et al., published in the Journal of Medical Economics, critiques escalating pharmaceutical expenditures amid new therapies like glucagon-like peptide-1 (GLP-1) receptor agonists for ty...
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Latest

Long-Term HPV Vaccine Effectiveness: Sustained Protection Against Cervical Disease

By João L. Carapinha

March 19, 2026

HPV vaccine effectiveness is demonstrated in new clinical and real-world data from Merck, showcasing the sustained protection of GARDASIL®9 (9-valent Human Papillomavirus [HPV] vaccine) and GARDASIL® (4-valent HPV vaccine) against HPV-related cancers and diseases. Key findings include vaccine eff...

Latest

TAVI Reimbursement Expansion for Low- and Intermediate-Risk Patients: A New Era in Cardiovascular...
The TAVI reimbursement expansion announced by Zorginstituut Nederland on March 10, 2026, includes transcatheter aortic valve implantation (TAVI) in...

Latest

PRIME Scheme Evaluation: Insights from Enhanced Development Tools Pilot
The PRIME Scheme Evaluation of the European Medicines Agency’s (EMA) PRIority Medicines (PRIME), launched in 2016, confirms early and enhanced regulatory support accelerates medicines for unmet needs. A two-year pilot (April 2023–March 2025) tested three new features—regulatory roadmap and produc...

Latest

EU Approves Imfinzi Gastric Cancer Treatment as Perioperative Immunotherapy

By João L. Carapinha

March 17, 2026

Imfinzi gastric cancer treatment has received European Commission approval for adults with resectable, early-stage and locally advanced (Stages II, III, IVA) gastric and gastroesophageal junction (GEJ) cancers. AstraZeneca’s Imfinzi (durvalumab), a PD-L1 inhibitor, combined with FLOT chemotherapy...

Global Updates

Methodological Gaps in Economic Evaluations of Vaccines: A Systematic Review

By João L. Carapinha

March 10, 2026

Economic evaluations of vaccines targeting multi-disease combinations, such as hepatitis A/B or measles-mumps-rubella (MMR), reveal critical methodological shortcomings in this systematic literature review. Synthesiz...

Global Updates

HERNEXEOS Lung Cancer Treatment: First FDA Approval for HER2-Mutant NSCLC

By HEOR Staff Writer

March 2, 2026

FDA Greenlights HERNEXEOS Lung Cancer Treatment as First-Line Option HERNEXEOS lung cancer treatment (zongertinib tablets), developed by

Global Updates

KEYTRUDA Padcev MIBC Survival: New Era in Treatment Revealed by KEYNOTE-B15 Trial Results
KEYTRUDA Padcev MIBC Survival Breakthrough in Cisplatin-Eligible Patients KEYTRUDA Padcev MIBC Survival benefits shone in the Phase 3 KEYNOTE-B15 trial, where perioperative KEYTRUDA (pembrolizumab) plus Padce...

Global Updates

Novartis Drug Discovery Innovation: Advancing Global Health Through Strategic R&D

By João L. Carapinha

February 26, 2026

Novartis drug discovery innovation is transforming global health through the Biomedical Research group's shift from siloed efforts to an integrated, patient-centric model targeting high-burden diseases in low- and middle-income countries (LMICs). Under Manju Ujjini, Head of Lead Discovery, key mi...

Europe

TAVI Reimbursement Expansion for Low- and Intermediate-Risk Patients: A New Era in Cardiovascular...

By João L. Carapinha

March 19, 2026

The TAVI reimbursement expansion announced by Zorginstituut Nederland on March 10, 2026, includes transcatheter aortic valve implantation (TAVI) in...
PRIME Scheme Evaluation: Insights from Enhanced Development Tools Pilot
The PRIME Scheme Evaluation of the European Medicines Agency’s (EMA) PRIority Medicines (PRIME), launched in 2016, confirms early and enhanced regulatory support accelerates medicines for unmet needs. A two-year pilot (April 2023–March 2025) tested three new features—regulatory roadmap and produc...
EU Approves Imfinzi Gastric Cancer Treatment as Perioperative Immunotherapy

By João L. Carapinha

March 17, 2026

Imfinzi gastric cancer treatment has received European Commission approval for adults with resectable, early-stage and locally advanced (Stages II, III, IVA) gastric and gastroesophageal junction (GEJ) cancers. AstraZeneca’s Imfinzi (durvalumab), a PD-L1 inhibitor, combined with FLOT chemotherapy...
Europe Life Sciences Competitiveness: Addressing Decline and Unlocking Potential
Europe life sciences competitiveness is under pressure, as detailed in the EFPIA report "Asses...

North America

Long-Term HPV Vaccine Effectiveness: Sustained Protection Against Cervical Disease

By João L. Carapinha

March 19, 2026

HPV vaccine effectiveness is demonstrated in new clinical and real-world data from Merck, showcasing the sustained protection of GARDASIL®9 (9-valent Human Papillomavirus [HPV] vaccine) and GARDASIL® (4-valent HPV vaccine) against HPV-related cancers and diseases. Key findings include vaccine eff...
FDA Biosimilar Approval Reforms: Accelerating Access and Reducing Drug Costs

By HEOR Staff Writer

March 11, 2026

The US Food and Drug Administration (FDA) has introduced biosimilar approval reforms to accelerate development and adoption, tackling biologic drug costs that exceeded 50% of total US drug spending in 2024. These biosimilar approval reforms address burdensome criteria stifling uptake, despite 82 ...
FDA Warning Letter Novo Nordisk Reveals Serious Compliance Failures in Adverse Drug Reporting
The U.S. Food and Drug Administration (FDA) issued the FDA Warning Letter Novo Nordisk dated March 5, 2026, to Novo Nordisk Inc. (NNI)...
Enhertu Early Breast Cancer: FDA Priority Review for Reducing Recurrence Risk

By João L. Carapinha

March 10, 2026

Enhertu (trastuzumab deruxtecan), developed by AstraZeneca and Daiichi Sankyo, has received P...

Sub-Saharan Africa

Aspen Pharmacare Financial Growth: Navigating H1 2026’s Transitional Financial Landscape

By HEOR Staff Writer

March 5, 2026

Aspen Pharmacare Financial Growth Powers Through Strategic Shifts Aspen Pharmacare's financial growth shines in its H1 2026 results, driven by resilient Commercial Pharmaceuticals,
South Africa’s Push for Local Lenacapavir Production to Enhance HIV Prevention
South Africa has launched a bold bid to enable local lenacapavir production, targeting the twice-yearly injectable long-acting HIV prevention drug from ...
SAHPRA GMP Compliance: Addressing Allegations Against Adcock Ingram’s Clayville Facility

By HEOR Staff Writer

February 25, 2026

SAHPRA GMP compliance at Adcock Ingram's Clayville facility has been reaffirmed by the South African Health Products Regulatory Authority (SAHPRA) in its
Pharmaceutical Tender Investigation Sparks Regulatory Scrutiny in South Africa

By João L. Carapinha

February 12, 2026

Pharmaceutical Tender Investigation Targets Ascendis, Pharma Q, and Sonke The Competition Commission of South Africa has launched a pharmaceutical tender investigation into manufacturers Ascendis, Pharma Q, and...