Increased Cardiovascular Implantable Electronic Device Infections

By Staff Writer

October 31, 2023

Understanding the Growing Concern

Cardiovascular Implantable Electronic Devices (CIEDs) are life-saving marvels of modern medicine. However, with over 300,000 patients receiving a new CIED implantation annually in the US alone, there has been a simultaneous surge in device infections. These infections can lead to substantial morbidity, with infected patients facing over 3-fold higher mortality compared to those without infections. Moreover, the financial burden on the healthcare system is significant.

The Significance of Prompt Intervention

The efficacy of antibiotics as a standalone treatment for CIED infection is limited. These factors have the potential to result in increased rates of infection relapse and fatality. In patients diagnosed with a definite CIED infection, the recommended course of action is the comprehensive extraction of both the device and lead. Research findings indicate that conducting extractions promptly following diagnosis leads to notable reductions in 1-year mortality rates, shorter durations of hospitalisation, and a decreased frequency of physician or hospital visits.

CIED infections and early intervention

There are concerns about the lack of compliance with guidelines for removing hardware from patients with CIED infections. The goal of this analysis was to measure the number of Medicare beneficiaries with CIED-related infections. These patients had lead extraction procedures between 2007 and 2019.  Additionally, the study attempted to analyse the resulting outcomes of these interventions. The researchers discovered that the process of lead extraction was linked to a decrease in mortality rates. Furthermore, they observed that conducting lead extraction at an earlier stage was correlated with even lower mortality rates compared to delaying the procedure.

This study identifies the need for comprehensive care in managing CIED infection. This includes identifying the infection, conducting a thorough examination, starting antibiotic treatment, making appropriate referrals, and deciding if extraction is needed. The study’s results highlight the urgent need to follow care guidelines more closely. They also stress the importance of improving quality within health systems. 

Reference url

Recent Posts

France’s HAS Denies Ribociclib Breast Cancer Therapy for Early HR+/HER2- Patients

By Staff Writer

August 12, 2025

Ribociclib breast cancer therapy has been closely scrutinized as an adjuvant treatment for patients with early-stage HR-positive, HER2-negative breast cancer at high risk of recurrence. If you’re wondering, “Why did France’s HAS reject reimbursement for ribociclib in this setting, and how might i...
FDA Approved Eye Drops: Lenz Therapeutics Launches VIZZ for Presbyopia Treatment

By Staff Writer

August 11, 2025

LENZ Therapeutics has secured FDA approval for VIZZ (aceclidine ophthalmic solution) 1.44%. These are the first FDA-approved eye drops designed to treat presbyopia in adults. They offer a once-daily improvement of near vision for up to 10 hours, and target approximately 128 million affected Ameri...
Building a Better Ecosystem for Digitally Enabled Diabetes Care in Europe

By João L. Carapinha

August 8, 2025

Digitally enabled diabetes care is rapidly transforming the management of Type 2 diabetes (T2D) across Europe. How does expanding access to these digital solutions improve health outcomes and reduce costs for individuals and health systems? Early evidence and recent policy recommendations (publis...