Medicare Drug Negotiations Target Ozempic and Ibrance for Price Cuts

By Rene Pretorius

January 17, 2025

Medicare drug negotiations represent a significant ongoing effort to lower prescription medication costs under the Inflation Reduction Act. The latest round of negotiations includes several high-cost drugs widely used by beneficiaries. Below is a summary of the key developments.

Key Drugs Selected for Price Negotiations

The Centers for Medicare and Medicaid Services (CMS) announced 15 drugs selected for the second round of Medicare price negotiations. Among them is semaglutide, the active ingredient in Ozempic, Rybelsus, and Wegovy, which Medicare covers for type 2 diabetes and cardiovascular disease risk reduction but not for obesity treatment. This selection is notable since Medicare spent $5.6 billion on semaglutide products in 2022. Another high-profile drug included is Ibrance (palbociclib), a widely used treatment for certain types of breast cancer. The list also features other high-cost medications commonly covered under Medicare Part D.

The Price Negotiation Process and Timeline

The negotiation process begins with CMS presenting an initial offer to drug manufacturers. Companies can submit counteroffers, leading to up to three rounds of discussions. The goal is to establish a mutually agreed-upon “maximum fair price” for each selected medication. The negotiated prices will take effect in January 2027, following the completion of negotiations in 2025.

Projected Impact on Drug Costs and Coverage

Lower negotiated prices aim to reduce financial strain on Medicare and its beneficiaries. Reduced costs may also facilitate broader policy changes, such as the potential expansion of Medicare coverage for anti-obesity medications. If drugs like semaglutide become more affordable, coverage for weight-loss treatments could become more financially viable.

Policy and Political Considerations

This announcement represents one of the Biden administration’s final major health policy actions. However, uncertainty remains regarding how a future administration may approach Medicare drug price negotiations and the broader policy debate on expanding Medicare coverage for anti-obesity treatments.

These Medicare negotiations mark another step toward controlling prescription drug costs and improving access to critical medications for millions of beneficiaries.

Reference url

Recent Posts

Aligning Medical Schemes with National Health Insurance South Africa

By João L. Carapinha

October 30, 2025

The National Health Insurance initiative in South Africa is advancing toward universal health coverage, and the recent CMS Annual Report 2024/25 highlighted the regulator's pivotal role in supporting this framework by integ...
Obesity Health Economics: Forecasting Trends and Costs in the US

By HEOR Staff Writer

October 29, 2025

Obesity health economics reveals a pressing public health crisis in the US, where rising prevalence drives massive costs and strains healthcare systems. If you're wondering how obesity impacts the economy, consider this: projections show annual expenses could surpass $1 trillion by 2040, fueled b...
Challenging the Narrative: Pharmaceutical Innovation Funding and Its Complex Dynamics

By João L. Carapinha

October 27, 2025

Pharmaceutical innovation funding in the UK faces scrutiny amid industry claims that low NHS spending deters investments, but this narrative overlooks key drivers like scientific talent, tax incentives, and operational efficiencies rather than drug prices alone. A recent Lancet article critiques ...