Innovative Technology Policy: Simulation Modelling in Healthcare

By Staff Writer

April 16, 2024

Introduction:

The healthcare industry is witnessing a paradigm shift, with simulation modelling playing a crucial role in shaping policies. This tool, which replicates real-world outcomes, is being used extensively to predict disease outcomes, assess impacts of policy changes, and estimate resource use associated with new interventions.

The Role of Simulation Modelling in Chronic Diseases:

In chronic diseases such as diabetes, simulation modelling is particularly beneficial for extrapolating long-term outcomes and costs not captured within the short durations of clinical trials. It also allows for the manipulation of various baseline parameters, which may be useful for policy makers from different jurisdictions.

Challenges with Existing Models:

Despite the well-validated results of existing models such as the Core Diabetes Model (CDM), these models are not always suitable for health technology assessment submissions in several jurisdictions, which require open-source code or special permission to use models that are not in Microsoft Excel or other high-level software.

The Introduction of the DEDUCE Model:

To aid in the economic evaluation of diabetes interventions, the DEtermination of Diabetes Utilities, Costs, and Effects (DEDUCE) model was developed. This model, built entirely within Microsoft Excel, offers transparency and the benefit of a more recent risk engine for type 2 diabetes.

Cost Implications of Diabetes Interventions:

The economic implications of diabetes interventions are significant and multifaceted. From direct costs associated with medical care and treatment to indirect costs due to productivity loss and disability, the financial burden of diabetes is substantial. Moreover, the costs associated with managing complications related to diabetes, such as cardiovascular disease and kidney disease, add to the economic strain. The DEDUCE model aids in the economic evaluation of diabetes interventions. This is offering a comprehensive view of the cost-effectiveness of various treatments and technologies.

Differences in Type 1 and Type 2 Diabetes Results:

The DEDUCE model uses different sets of risk equations to predict outcomes for people with type 1 and type 2 diabetes. For type 2 diabetes, the model uses the Risk Equations for Complications Of type 2 Diabetes (RECODe), which has been validated extensively. On the other hand, for type 1 diabetes, the model uses the Sheffield type 1 Diabetes Model equations. The model’s performance varied between the two types of diabetes, with a generally higher predictive agreement for type 2 diabetes outcomes. This highlights the need for further research and refinement of risk equations for type 1 diabetes.

Assessing the Accuracy and Validity of the DEDUCE Model:

A recent study compared the DEDUCE model’s predictions with real outcomes from various external studies and trials to evaluate its accuracy and validity. The model generally excelled in cross-validation. In several comparisons with historical external models, it ranked either first or second.

Conclusion:

The DEDUCE model is a powerful tool for predicting diabetes-related complications and evaluating the cost-effectiveness of diabetes interventions. Future work to compare these results in a new Mount Hood challenge may bolster these results, providing valuable insight into the cost-effectiveness of diabetes technologies for various stakeholders.

Reference url

Recent Posts

semaglutide NAION risk
    

Semaglutide NAION Risk: EMA Review Initiated Amid Conflicting Evidence

🔍 Is semaglutide linked to vision loss?

The European Medicines Agency’s PRAC is currently reviewing the potential risk of non-arteritic anterior ischemic optic neuropathy (NAION) associated with semaglutide-containing medicines, including popular treatments like Ozempic and Wegovy. With recent studies yielding conflicting evidence, this review is crucial for patient safety and the future of these therapies.

Read the full article to understand the implications and what this could mean for healthcare providers and patients alike!

#SyenzaNews #Pharmaceuticals #HealthcarePolicy

cervical cancer screening
        

Cost-Effective Cervical Cancer Screening Strategies for Women with HIV in KwaZulu-Natal

💡 *Are single-visit cervical cancer screenings the key to better health outcomes in high HIV prevalence areas?*
A recent study from KwaZulu-Natal, South Africa reveals that repeat single-visit cervical cancer screening using HPV DNA testing is not only the most effective but also the most cost-effective approach for women living with HIV. This aligns with WHO recommendations for comprehensive cervical cancer elimination strategies.

Explore the insights and implications of this vital research that could transform cervical cancer prevention in resource-limited settings.

#SyenzaNews #HealthEconomics #oncology #GlobalHealth

EU Health Technology Assessment
          

Advancing EU Health Technology Assessment: Insights from the HAG Meeting

💡 How can the EU Health Technology Assessment reshape healthcare delivery?

The recent meeting of the Heads of HTA Agencies Group heralds a new era with the operationalization of the EU’s Health Technology Assessment Regulation, aiming to streamline processes and enhance collaboration across member states.

This initiative promises to improve data transparency, foster innovative health technologies, and ultimately, drive better patient outcomes.

Curious to learn more about these significant updates and what they mean for the future of health assessments in the EU? Jump into the full article!

#SyenzaNews #HealthTech #HealthEconomics #DigitalTransformation

When you partner with Syenza, it’s like a Nuclear Fusion.

Our expertise are combined with yours, and we contribute clinical expertise and advanced degrees in health policy, health economics, systems analysis, public finance, business, and project management. You’ll also feel our high-impact global and local perspectives with cultural intelligence.

SPEAK WITH US

CORRESPONDENCE ADDRESS

1950 W. Corporate Way, Suite 95478
Anaheim, CA 92801, USA

© 2025 Syenza™. All rights reserved.