Global HIV/AIDS and Sub-Saharan Africa breakthroughs

By Crystal Lubbe

November 28, 2024

The article from News-Medical.net, titled “IHME Study Reveals Significant Progress and Gaps in the Global Fight Against HIV/AIDS,” based on a study by the Institute for Health Metrics and Evaluation (IHME), offers a comprehensive analysis of HIV/AIDS global progress , with a particular focus on Sub-Saharan Africa. This region continues to bear the heaviest burden of the epidemic, making its progress crucial to global efforts.

Significant Progress in Sub-Saharan Africa

  • Sub-Saharan Africa has led the global decline in HIV-related deaths and new infections, thanks to the widespread availability and effectiveness of antiretroviral therapy (ART). The region, which hosts 72.6% of the global HIV population, has seen life expectancy recover after previous declines due to the epidemic.
  • Global deaths from HIV/AIDS have halved over the past decade, with ART significantly reducing mortality rates from a peak of nearly 2 million per year in the mid-2000s.

Persistent Challenges

  • Despite these advancements, Sub-Saharan Africa still faces significant challenges. HIV/AIDS remains the leading cause of death in some countries, heavily impacting life expectancy.
  • Gender disparities persist, with women in the region being infected earlier and living longer than men, yet facing higher risks due to gender inequality and social norms.

Global Impact and Challenges

  • While there has been significant global progress in reducing new HIV infections and AIDS-related deaths, current trends suggest the world is not on track to meet the UNAIDS 2030 targets of reducing these figures by 90%.
  • Regions such as North Africa and the Middle East are seeing increases in new infections and deaths, with only 67% of people aware of their HIV status, 50% accessing ART, and 45% achieving viral suppression.
  • More than a million new HIV infections occur annually, and a quarter of the 40 million people living with HIV are not receiving treatment, highlighting the need for expanded ART access and improved testing.

Strategic Interventions and Funding

  • The global community must strengthen public health programs, such as the US President’s Emergency Plan for AIDS Relief (PEPFAR). It should also expand prevention services and implement effective care models.
  • Addressing the health financing gap, particularly in Africa, is critical for scaling up prevention and treatment services. In 2023, $14.7 billion was spent on global HIV/AIDS efforts. However strategic and equitable interventions are needed to meet the UNAIDS 2030 goals.

Role of Community Health Workers

Community health workers are essential in the fight against HIV/AIDS. They extend care to remote and underserved populations. By doing so, they help bridge treatment gaps and sustain progress. Their work is vital for reaching those who might otherwise lack access to healthcare services.

In summary, the IHME study emphasises that while substantial progress has been made, particularly in Sub-Saharan Africa, significant challenges remain. To meet the UNAIDS 2030 targets the world must accelerate efforts in prevention, treatment, and care.

Reference url

Recent Posts

Mental Health Policy Integration: A Cross-Sector Imperative for Well-being and Productivity

By João L. Carapinha

July 31, 2025

The purpose of this update is to review a recent Lancet editorial (linked below) on mental health policy integration in public policy frameworks. The article “Mental health in all policies” emphasizes that mental health influences individual well-being, societal cohesion, and economic productivit...
Novartis Gains Approval for Groundbreaking Malaria Treatment for Infants

By Rene Pretorius

July 30, 2025

In this article we review Swissmedic's approval of Novartis' Coartem Baby. It is the first malaria treatment for infants under 4.5 kilograms. This novel formulation addresses a critical gap in antimalarial care. Existing treatments were unsuitable due to dosing and metabolism concerns in young in...
ViiV Healthcare Licensing: Expanding Access to Long-Acting HIV Treatment in Low-Income Countries
ViiV Healthcare has expanded its voluntary licensing agreement with the Medicines Patent Pool. The update now includes access to long-acting injectable cabotegravir (CAB LA) for HIV treatment. This allows generic manufacturers to supply the therapy in 133 low- and middle-income countries (LMICs)....