Global Pull Incentive Needed to Future-Proof Antibiotic Innovation, Says OHE Report

By Staff Writer

April 12, 2023

A new report highlights the pervasive market failure in the antibiotics space and proposes a globally aligned, value-based, fully-delinked pull incentive to future-proof antibiotic innovation. The mechanism would involve payers paying manufacturers a pre-specified subscription fee, based on the value of the antibiotic, over a pre-specified period, regardless of the volume of antibiotics used. The report suggests that the size of a global pull incentive should be calculated by aggregating revenue from all countries where the product is sold, with a 10-year ‘subscription’ type payment estimated to be $4.2 billion. Eligible products should be selected based on globally aligned criteria, including the unmet need to be addressed and a target product profile. Value assessment must be local, and its methodology must distinguish between higher and lower value products. The report concludes that investment in research is needed in the short term to develop communities of practice around economic modelling for antibiotics with a view to generating methods and finding evidence sources that will enable population benefits to be estimated using QALY-based modelling with appropriate adjustment for risk aversion.

Reference url

Recent Posts

U.S. withdraws from WHO
     

U.S. Withdraws from WHO: Impact on Global Health Security and Relations

🚨 *What does the U.S. withdrawing from the WHO mean for global health?*
President Trump’s executive order to begin the withdrawal process raises serious concerns about the future of global health security. From financial disparities to a shift in international partnerships, the implications could reshape our collective ability to combat pandemics and health crises.

Dive into our article to understand the potential impacts on health outcomes and the quest for new alliances.

#SyenzaNews #globalhealth #healthcarepolicy

semaglutide NAION risk
    

Semaglutide NAION Risk: EMA Review Initiated Amid Conflicting Evidence

🔍 Is semaglutide linked to vision loss?

The European Medicines Agency’s PRAC is currently reviewing the potential risk of non-arteritic anterior ischemic optic neuropathy (NAION) associated with semaglutide-containing medicines, including popular treatments like Ozempic and Wegovy. With recent studies yielding conflicting evidence, this review is crucial for patient safety and the future of these therapies.

Read the full article to understand the implications and what this could mean for healthcare providers and patients alike!

#SyenzaNews #Pharmaceuticals #HealthcarePolicy

cervical cancer screening
        

Cost-Effective Cervical Cancer Screening Strategies for Women with HIV in KwaZulu-Natal

💡 *Are single-visit cervical cancer screenings the key to better health outcomes in high HIV prevalence areas?*
A recent study from KwaZulu-Natal, South Africa reveals that repeat single-visit cervical cancer screening using HPV DNA testing is not only the most effective but also the most cost-effective approach for women living with HIV. This aligns with WHO recommendations for comprehensive cervical cancer elimination strategies.

Explore the insights and implications of this vital research that could transform cervical cancer prevention in resource-limited settings.

#SyenzaNews #HealthEconomics #oncology #GlobalHealth

When you partner with Syenza, it’s like a Nuclear Fusion.

Our expertise are combined with yours, and we contribute clinical expertise and advanced degrees in health policy, health economics, systems analysis, public finance, business, and project management. You’ll also feel our high-impact global and local perspectives with cultural intelligence.

SPEAK WITH US

CORRESPONDENCE ADDRESS

1950 W. Corporate Way, Suite 95478
Anaheim, CA 92801, USA

© 2025 Syenza™. All rights reserved.