Global Partnerships SCD in Africa

By Crystal Lubbe

March 19, 2025

How can global partnerships transform care for sickle cell disease in Africa?  This article highlights the importance of global partnerships SCD in improving sickle cell disease (SCD) care in Africa. It emphasises the role of the SickleInAfrica consortium. High-level engagements at forums like the United Nations General Assembly and the US-Africa Leaders’ Summit have promoted awareness and partnerships for SCD research and care. The consortium has established a large patient registry and adapted clinical guidelines, improving SCD management across Africa.

Key Insights

  • Global Partnerships: The article emphasises the significance of global partnerships SCD from local to global levels. These partnerships advance SCD care and research. They facilitate cross-border dialogues, policy advocacy, and the establishment of SCD Centres of Excellence.
  • Scientific Innovations: Scientific innovations, such as genomics and advanced therapies, are crucial for improving SCD outcomes. The SickleInAfrica consortium has made significant strides in these areas.
  • Patient Registry and Clinical Guidelines: The consortium has achieved key milestones, including a comprehensive patient registry and contextually adapted clinical guidelines. These enhance SCD management across participating countries.

Background Context

Sickle cell disease is a major public health issue in Africa. Over 78% of global cases occur in sub-Saharan Africa. Historically, African health systems have struggled to provide optimal care, leading to high mortality and morbidity rates. Initiatives like the SickleInAfrica consortium aim to address these gaps through partnerships and scientific advancements. For example, Muhimbili University of Health and Allied Sciences (MUHAS) in Tanzania has developed significant SCD research programs. These include advanced therapy programs focused on patient engagement and advocacy.

Implications

The purpose of this content is to outline the implications of strengthening global partnerships SCD for SCD care. These implications are multifaceted:

  • Health Economics: Improved access to advanced therapies and better SCD management can reduce healthcare costs. This includes costs from frequent hospitalisations and complications, enhancing health outcomes and economic productivity.
  • Health Outcomes: Enhanced care and research collaboration can improve survival rates and quality of life for SCD patients. This contributes to achieving health-related Sustainable Development Goals.
  • Policy and Advocacy: Establishing SCD Centres of Excellence and policy advocacy efforts can ensure sustainable support for SCD care and research. This fosters equitable access to treatments across Africa.

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