Cardiovascular Disease Risk Assessment – A new approach using AI

By Michael Awood

September 20, 2023

Artificial intelligence (AI) has a far reaching grasp. It continues to extend its reach into the healthcare space. One of the areas that its having a profound impact is in the space of early disease detection. Its now changing the way we predict and manage cardiovascular disease (CVD), which is a leading cause of mortality worldwide. Traditional risk factors such as age, sex, and family history are combined with clinical parameters like glucose and cholesterol levels to calculate risk, but these methods fall short in assessing vascular condition directly and efficiently.

AI has paved the way for a more cost-effective tool for CVD risk assessment: ocular imaging. The eye’s microvascular system, particularly the retinal part, shares similarities with the brain and cardiovascular system. Research has shown a strong correlation between the retina and CVD. AI has been used to detect ocular diseases, and now, it is being applied to predict CVD from ocular images.

Despite these advancements, challenges remain showing significant limitations due to population variability. The limited availability of high-quality labelled data for AI model training and validation is also major issue. There is also a need for prospective trials to validate the model’s usefulness and safety in real-world scenarios.

The successful transition of AI-ocular image analysis from theory to real-world application requires addressing various challenges, including conducting cost-benefit analyses of AI models, securing funding sources, establishing information technology infrastructure, fostering social acceptance, managing clinical workflow changes, and navigating regulatory issues.

In conclusion, AI in ocular imaging offers a promising tool for CVD risk assessment. However, further research and collaboration are needed to address the challenges and bring this tool to clinical application. 



Reference url

Recent Posts

regulatory validation taletrectinib
Advancing Regulatory Validation Taletrectinib for Enhanced NSCLC Treatment

By João L. Carapinha

June 30, 2026

The MHRA’s validation of Nuvation Bio’s marketing authorisation application marks an important regulatory validation taletrectinib for adults with advanced ROS1-positive non-small cell lung cancer. This milestone, achieved via the International Recognition Procedure in parallel with EMA review, f...
Portuguese Biotech Innovation
Global Impact of Portuguese Biotech Innovation

By João L. Carapinha

June 30, 2026

Portuguese Biotech Innovation has matured into a compelling global force, with Solfarcos marking a decade of translating University of Minho research into commercial technologies that span cosmetics and pharmaceuticals. The Braga-based spin-off has built a unified platform of peptides and protein...
cannabis regulatory exploitation
Exposing Cannabis Regulatory Exploitation in Portugal’s Medicinal Sector

By João L. Carapinha

June 30, 2026

Portugal’s medicines regulator INFARMED has been shaken by a major case of cannabis regulatory exploitation in which criminal networks weaponised medicinal cannabis licences to traffic drugs on an industrial scale. Insufficient inspectors, rapid sector growth and the recruitment of former agency ...