AI and Annotated Medical Images – OpenPath, PLIP, and “Medical Twitter”

By Michael Awood

September 1, 2023

The lack of available annotated medical images has historically hindered healthcare innovation. However, a solution is emerging as healthcare professionals start to share anonymised images and insights on public platforms – which includes the social media site previously known as Twitter (X). This has led to the creation of OpenPath, a comprehensive dataset of over 200,000 pathology images coupled with natural language descriptions, marking it as the largest public dataset of its kind.

Researchers have used OpenPath to develop Pathology Language–Image Pre-training (PLIP), a multimodal AI trained on this dataset. PLIP has demonstrated impressive results in zero-shot learning and transfer learning for classifying new pathology images across various tasks. Additionally, PLIP enables users to locate similar cases using either image or natural language search, encouraging knowledge sharing.

The researchers collected over 240,000 public pathology images using popular pathology-related hashtags and expanded the collection with data from other online sources. After thorough data quality checks, they assembled over 200,000 pathology image-text pairs named OpenPath, which they used to develop the versatile PLIP.

PLIP outperformed previous models in tasks such as zero-shot learning, linear probing, and text-to-image and image-to-image retrieval. Unlike other digital pathology machine learning methods, PLIP can adapt to new datasets and provide zero-shot predictions based on any text input, making it a flexible tool for potential new disease subtypes.

The study did note some limitations, including irrelevant data in the image-text pairs and challenges in accounting for varying magnification levels and staining styles. However, researchers are optimistic that PLIP can adjust to images with diverse magnification levels and staining protocols. They expect that OpenPath and PLIP will significantly contribute to advancing AI in pathology and encourage a data-focused approach in this area.

Reference url

Recent Posts

allopurinol Marfan syndrome orphan
       

Allopurinol Designated an Orphan Drug for Marfan Syndrome

🌟 What does the EMA’s orphan drug designation for allopurinol mean for those impacted by Marfan syndrome?

This groundbreaking move highlights a significant step forward in tackling rare diseases, offering hope to patients with limited treatment options. Allopurinol, traditionally used for gout, shows promise in addressing life-threatening aortic complications associated with Marfan syndrome, thanks to its antioxidant properties.

Dive into the implications of this development for healthcare innovation, patient access, and the future of rare disease treatment!

#SyenzaNews #HealthEconomics #Innovation #MarketAccess

marstacimab hemophilia B
                

NICE’s Approval of Marstacimab for Hemophilia B: Transforming Treatment Landscapes and Economic Implications

💡 Are we witnessing a paradigm shift in hemophilia treatment?

The recent recommendation from NICE for marstacimab as a novel therapy for severe hemophilia B is a game-changer. With its ability to provide effective prophylaxis while potentially lowering treatment costs, this could reshape patient care and health economics in this space.

Dive into the implications this has for patients and healthcare providers, and why marstacimab’s approval could be a pivotal moment for hemophilia management.

Explore the full article for deeper insights!

#SyenzaNews #HealthEconomics #HealthcareInnovation #MarketAccess

HPV-related cancer trends
    

HPV-Related Cancer Trends in South Africa 2011-2021

🌍 Are we witnessing a rise in HPV-related cancer in South Africa?

A recent analysis of data from the South African National Cancer Registry highlights concerning trends: while cervical cancer rates are declining, there’s an alarming rise in non-cervical anogenital cancers. This underscores the urgent need for enhanced cancer prevention and access to efficient healthcare services in the country.

Dive into the findings and explore the implications for health systems and policies.

#SyenzaNews #HealthEconomics #HealthcareInnovation #GlobalHealth

When you partner with Syenza, it’s like a Nuclear Fusion.

Our expertise are combined with yours, and we contribute clinical expertise and advanced degrees in health policy, health economics, systems analysis, public finance, business, and project management. You’ll also feel our high-impact global and local perspectives with cultural intelligence.

SPEAK WITH US

CORRESPONDENCE ADDRESS

1950 W. Corporate Way, Suite 95478
Anaheim, CA 92801, USA

© 2025 Syenza™. All rights reserved.