Challenges in Accelerating Innovative Paediatric Medicine

By Rene Pretorius

April 11, 2025

Summary

How can we advance innovative paediatric medicine and care in Europe?  Public-private collaborations like the Innovative Health Initiative (IHI) and its predecessor, the Innovative Medicines Initiative (IMI), play a key role. These initiatives have improved paediatric medicines, clinical trial infrastructures, and health solutions for children. However, challenges remain in developing paediatric medical devices and diagnostics.

 

Key Insights

  • Multi-stakeholder Collaboration: The IHI and IMI unite diverse stakeholders (industry, academia, patients, regulators) to address paediatric development challenges.
  • Clinical Trial Infrastructure: Projects like conect4children have created pan-European networks for better paediatric clinical trials.
  • Regulatory Impact: The EU Pediatric Regulation has boosted clinical trials and medicines for children, but gaps in device development persist.

 

The State of Innovative Paediatric Medicine in Europe

The Innovative Health Initiative (IHI) and its predecessor, the Innovative Medicines Initiative (IMI), have significantly advanced pediatric research in Europe. These public-private partnerships have united academia, healthcare providers, industry, patients, regulators, and health technology assessment bodies to tackle challenges in developing pediatric medicines. Despite progress, challenges to innovation in peadiatric medicine persist, specifically:

  • Most devices are designed for adults and later adapted for children, often without robust testing in paediatric populations.

  • There is a lack of age-appropriate device sizes and functionalities, particularly for neonates and infants.

  • Few incentives exist for manufacturers to invest in paediatric-specific device innovation due to small market size, high development costs, and complex regulatory requirements.

  • Limited collaboration between engineers, clinicians, and regulators slows progress.

  • Fragmented data and insufficient clinical trial infrastructure for children further hinder development.

These gaps persist due to regulatory, economic, and technical barriers that remain unresolved.

 

The Future for Innovative Peadiatrics

To accelerate innovation in paediatric medicine, stakeholders must align early, invest in child-specific research, and streamline regulatory pathways—ensuring that safe, effective, and age-appropriate treatments reach children without delay.

  • Increased Innovation and Access: Public-private partnerships can speed up paediatric treatment development, improving outcomes and cutting costs.
  • Global Collaboration: Low patient numbers require global cooperation for sufficient data and effective treatments.
  • Policy Impact: Regulatory frameworks and incentives are vital to drive investment in pediatric research.

For more insights, check the original source here.

Reference url

Recent Posts

DTC telehealth partnerships
           

DTC Telehealth Partnerships: Navigating Risks in Pharma’s Digital Expansion

🚀 Are pharmaceutical companies’ DTC telehealth partnerships reshaping healthcare for better or worse?

Recent findings from the “DTC Investigation 2025” report reveal key insights into the high prescription rates and potential risks of these digital platforms operated by giants like Pfizer and Eli Lilly. Alarmingly, inadequate clinical safeguards raise questions about patient safety, prescribing practices, and cost implications.

Dive into this critical discussion about the intersection of digital health and pharmaceutical practices, and explore what it means for the future of patient care.

#SyenzaNews #DigitalHealth #HealthEconomics #HealthcarePolicy

MAF Test breast cancer
       

MAF Test Breast Cancer: Revolutionizing Personalized Treatment in Spanish Oncology

🌟 How can personalized medicine transform breast cancer treatment in Spain?

The recent rollout of the MAF Test breast cancer in leading Spanish hospitals is set to revolutionize patient care by enabling targeted treatment strategies. This innovative molecular assay not only identifies patients who will benefit from bisphosphonates but also spares those for whom the treatment may be harmful, ultimately improving outcomes for thousands.

Dive into the article to discover how this approach aligns with global trends in oncology and enhances healthcare resource allocation.

#SyenzaNews #precisionmedicine #HealthEconomics #innovation

ribociclib breast cancer guidance
           

NICE’s Ribociclib Breast Cancer Guidance: A New Era for High-Risk Patients in the NHS

🌟 Are we on the brink of transforming breast cancer treatment?

NICE’s latest guidance endorsing ribociclib in combination with an aromatase inhibitor marks a significant advancement for adults facing high-risk early breast cancer. This decision not only promises enhanced survival outcomes but also expands treatment options for patients historically limited to conventional therapies.

Dive into the details of this important development and learn how it may revolutionize patient care in the oncology landscape.

#SyenzaNews #oncology #costeffectiveness #MarketAccess

When you partner with Syenza, it’s like a Nuclear Fusion.

Our expertise are combined with yours, and we contribute clinical expertise and advanced degrees in health policy, health economics, systems analysis, public finance, business, and project management. You’ll also feel our high-impact global and local perspectives with cultural intelligence.

SPEAK WITH US

CORRESPONDENCE ADDRESS

1950 W. Corporate Way, Suite 95478
Anaheim, CA 92801, USA

JOIN NEWSLETTER

© 2025 Syenza™. All rights reserved.