A Comprehensive COVID-19 Treatments Review

By HEOR Staff Writer

October 20, 2023

COVID-19 Treatments: A Race Against Time

The COVID-19 pandemic has led to an urgent need for effective treatments of this unknown disease. As of January 2023, there have been over 620 million confirmed cases of the virus and more than six-and-a-half million deaths worldwide. In the UK alone, the numbers are staggering with more than 24 million cases and nearly 200,000 deaths during this time.

COVID-19 Treatments Review

Various treatments have been developed and used to help people who have been hospitalised due to COVID-19 or are at high risk of needing hospitalisation. These include casirivimab/imdevimab, tocilizumab, remdesivir, baricitinib, and baricitinib with remdesivir for hospitalised patients. For patients at high risk, treatments include casirivimab/imdevimab, molnupiravir, nirmatrelvir/ritonavir, remdesivir, sotrovimab, and tixagevimab/cilgavimab.

Evaluating Clinical Efficacy and Cost-effectiveness

The objective of this study was to summarise the current knowledge related to the clinical efficacy of these interventions and to conduct an economic evaluation that estimates the cost-effectiveness of each intervention against standard of care (SoC).

Despite the urgency, these treatments have not received positive guidance from the National Institute of Health and Care Excellence (NICE) before being routinely used. As the pandemic subsides, there is more need for a formal evaluation of these treatments.

The results of the study, however, should be treated with caution due to changes in the conditions when the pivotal studies were undertaken and the current conditions in terms of the SoC, the percentage of people who have been vaccinated and a change in the dominant SARS-CoV-2 variant.

Reference url

Recent Posts

Launch of TrumpRx Drug Pricing: Savings on Essential Medications

By João L. Carapinha

February 6, 2026

TrumpRx Drug Pricing Launches with Massive Discounts President Donald J. Trump announced the launch of TrumpRx.gov on February 5, 2026, as a cornerstone of TrumpRx drug pricing reforms, enabling American patients to access signif...
Healthcare Innovation Trends Shaping the Future: Insights from the J.P. Morgan Conference
Healthcare Innovation Trends Spotlighted at J.P. Morgan Conference Healthcare innovation trends took center stage at the J.P. Morgan Healthcare Conference, the industry's largest global event, where investors, leaders...
Novo Nordisk Growth Projections: Insights on 2025 Performance and 2026 Outlook

By João L. Carapinha

February 4, 2026

Novo Nordisk's company announcement details 2025 financial results and a 2026 outlook, with Novo Nordisk growth projections highlighting 10% sales growth and 6% oper...