Null Link Confirmed: Prenatal Acetaminophen Autism Risk Study in Denmark

By HEOR Staff Writer

April 17, 2026

A major nationwide Danish cohort study has found no link between maternal acetaminophen use during pregnancy and autism in children. The new evidence on prenatal acetaminophen autism risk should reassure clinicians and expectant mothers, as both population-wide and sibling-controlled analyses sho...
Amyloid-Beta Treatment Impact: Limited Clinical Benefits and Increased Risks in Early Alzheimer’s...
Amyloid-Beta Treatment Impact on people with early Alzheimer’s disease is minimal, according to a major new Cochrane review. The analysis of 17 randomized controlled trials involving more than 20,000 participants found that amyloid-beta-targeting monoclonal antibodies deliver only trivial improve...
HIV Prevention Partnerships: Expanding Access to Lenacapavir for Global Impact
HIV Prevention Partnerships between PEPFAR, The Global Fund, and Gilead Sciences are accelerating access to twice-yearly injectable lenacapavir for HIV pre-exposure prophylaxis (PrEP) in high-burden countries. Unprecedented Speed to Sub-Saharan Africa This additional i...
Escalating Public Spending: Semaglutide Off-Label Use Sparks €250 Million Fraud Investigation in ...
Semaglutide off-label use for weight loss is at the centre of a suspected €250 million fraud uncovered by Portugal’s Judicial Police within the National Health Service (SNS). According to the investigation reported on 15 April 2026, roughly half of all public spending on Ozempic (semaglutide) bet...
Advancing B7-H3 Targeted Therapy for Relapsed Extensive-Stage Small Cell Lung Cancer

By HEOR Staff Writer

April 15, 2026

The FDA’s Priority Review of ifinatamab deruxtecan was recently announced, a potential first-in-class B7-H3 targeted therapy. The Biologics License Application for ifinatamab deruxtecan (I-DXd), a B7-H3 directed DXd antibody drug conjugate (ADC), has been accepted with a Prescription Drug User Fe...
Advancing Inclusive Healthcare Strategies Through Social Impact and Sustainability
In this update we examine how Novartis is embedding inclusive healthcare strategies into its core business by launching ambitious long-term Social Impact and Sustainability (SI&S) targets that reach to 2040. These targets integrate innovation, access to medicines, global health, environmental...
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Latest

Null Link Confirmed: Prenatal Acetaminophen Autism Risk Study in Denmark

By HEOR Staff Writer

April 17, 2026

A major nationwide Danish cohort study has found no link between maternal acetaminophen use during pregnancy and autism in children. The new evidence on prenatal acetaminophen autism risk should reassure clinicians and expectant mothers, as both population-wide and sibling-controlled analyses sho...

Latest

Amyloid-Beta Treatment Impact: Limited Clinical Benefits and Increased Risks in Early Alzheimer’s...
Amyloid-Beta Treatment Impact on people with early Alzheimer’s disease is minimal, according to a major new Cochrane review. The analysis of 17 randomized controlled trials involving more than 20,000 participants found that amyloid-beta-targeting monoclonal antibodies deliver only trivial improve...

Latest

HIV Prevention Partnerships: Expanding Access to Lenacapavir for Global Impact
HIV Prevention Partnerships between PEPFAR, The Global Fund, and Gilead Sciences are accelerating access to twice-yearly injectable lenacapavir for HIV pre-exposure prophylaxis (PrEP) in high-burden countries. Unprecedented Speed to Sub-Saharan Africa This additional i...

Latest

Escalating Public Spending: Semaglutide Off-Label Use Sparks €250 Million Fraud Investigation in ...
Semaglutide off-label use for weight loss is at the centre of a suspected €250 million fraud uncovered by Portugal’s Judicial Police within the National Health Service (SNS). According to the investigation reported on 15 April 2026, roughly half of all public spending on Ozempic (semaglutide) bet...

Global Updates

HIV Prevention Partnerships: Expanding Access to Lenacapavir for Global Impact
HIV Prevention Partnerships between PEPFAR, The Global Fund, and Gilead Sciences are accelerating access to twice-yearly injectable lenacapavir for HIV pre-exposure prophylaxis (PrEP) in high-burden countries. Unprecedented Speed to Sub-Saharan Africa This additional i...

Global Updates

Advancing Inclusive Healthcare Strategies Through Social Impact and Sustainability

By João L. Carapinha

April 15, 2026

In this update we examine how Novartis is embedding inclusive healthcare strategies into its core business by launching ambitious long-term Social Impact and Sustainability (SI&S) targets that reach to 2040. These targets integrate innovation, access to medicines, global health, environmental...

Global Updates

Utah’s AI Medication Prescribing Risks: Navigating the Challenges of Autonomous Systems

By HEOR Staff Writer

April 14, 2026

In this update we examine how Utah’s groundbreaking partnership with an AI company has introduced serious AI medication prescribing risks by authorizing unsupervised prescribing of nearly 200 medications. In January 2026, Utah partnered with Doctronic to deploy the first system in the United S...

Global Updates

Advancements in Pulsed Field Ablation: The VARIPULSE Pro Platform Launch

By HEOR Staff Writer

April 9, 2026

Johnson & Johnson’s launchs the VARIPULSE Pro Platform in Europe. Pulsed field ablation has advanced significantly with the introduction of a new pulse sequence that delivers ablation lesions five times faster than the previous version while maintaining equivalent lesion quality and the estab...

Europe

Null Link Confirmed: Prenatal Acetaminophen Autism Risk Study in Denmark

By HEOR Staff Writer

April 17, 2026

A major nationwide Danish cohort study has found no link between maternal acetaminophen use during pregnancy and autism in children. The new evidence on prenatal acetaminophen autism risk should reassure clinicians and expectant mothers, as both population-wide and sibling-controlled analyses sho...
Amyloid-Beta Treatment Impact: Limited Clinical Benefits and Increased Risks in Early Alzheimer’s...
Amyloid-Beta Treatment Impact on people with early Alzheimer’s disease is minimal, according to a major new Cochrane review. The analysis of 17 randomized controlled trials involving more than 20,000 participants found that amyloid-beta-targeting monoclonal antibodies deliver only trivial improve...
Escalating Public Spending: Semaglutide Off-Label Use Sparks €250 Million Fraud Investigation in ...
Semaglutide off-label use for weight loss is at the centre of a suspected €250 million fraud uncovered by Portugal’s Judicial Police within the National Health Service (SNS). According to the investigation reported on 15 April 2026, roughly half of all public spending on Ozempic (semaglutide) bet...
Advancing Inclusive Healthcare Strategies Through Social Impact and Sustainability

By João L. Carapinha

April 15, 2026

In this update we examine how Novartis is embedding inclusive healthcare strategies into its core business by launching ambitious long-term Social Impact and Sustainability (SI&S) targets that reach to 2040. These targets integrate innovation, access to medicines, global health, environmental...

North America

Advancing B7-H3 Targeted Therapy for Relapsed Extensive-Stage Small Cell Lung Cancer
The FDA’s Priority Review of ifinatamab deruxtecan was recently announced, a potential first-in-class B7-H3 targeted therapy. The Biologics License Application for ifinatamab deruxtecan (I-DXd), a B7-H3 directed DXd antibody drug conjugate (ADC), has been accepted with a Prescription Drug User Fe...
Advancing Access: Generic Dapagliflozin Approval Enhanced for Type 2 Diabetes Treatment

By João L. Carapinha

April 14, 2026

The U.S. Food and Drug Administration has issued the generic dapagliflozin approval, clearing the first generic versions of FARXIGA (dapagliflozin) tablets. This decision significantly improves affordability and access to an important SGLT2 inhibitor for adults with type 2 diabetes. ...
Utah’s AI Medication Prescribing Risks: Navigating the Challenges of Autonomous Systems
In this update we examine how Utah’s groundbreaking partnership with an AI company has introduced serious AI medication prescribing risks by authorizing unsupervised prescribing of nearly 200 medications. In January 2026, Utah partnered with Doctronic to deploy the first system in the United S...
Expansion of Community Health Programs by Novartis to Tackle Global Health Disparities

By João L. Carapinha

April 9, 2026

Novartis’ ambitious scale-up of community health programs aims to close critical gaps in cardiovascular and cancer care. Announced on April 9, 2026, the initiative will expand these community health programs from 11 to more than 30 countries by 2030, including five major U.S. cities, with a stron...

Sub-Saharan Africa

HIV Prevention Partnerships: Expanding Access to Lenacapavir for Global Impact

By João L. Carapinha

April 17, 2026

HIV Prevention Partnerships between PEPFAR, The Global Fund, and Gilead Sciences are accelerating access to twice-yearly injectable lenacapavir for HIV pre-exposure prophylaxis (PrEP) in high-burden countries. Unprecedented Speed to Sub-Saharan Africa This additional i...
Expansion of Community Health Programs by Novartis to Tackle Global Health Disparities

By João L. Carapinha

April 9, 2026

Novartis’ ambitious scale-up of community health programs aims to close critical gaps in cardiovascular and cancer care. Announced on April 9, 2026, the initiative will expand these community health programs from 11 to more than 30 countries by 2030, including five major U.S. cities, with a stron...
Enhancing Obesity Treatment Pricing in South Africa Through Competitive Strategies

By João L. Carapinha

April 2, 2026

Novo Nordisk has cut the price of Wegovy for the second time in South Africa, making obesity treatment pricing South Africa a key focus for improved patient access. The latest reductions, announced on 25 March 2026, lower the lowest injectable dose from 3,090 rand to 1,873 rand and the highest do...
South Africa Health Reform: Revitalizing the Crisis-Stricken Sector

By João L. Carapinha

March 26, 2026

South Africa health reform is urgently needed to reverse the deepening crisis in the country’s public and private health sectors. Sustained real-term declines in public per-capita spending, massive provincial debt, critical staff shortages, and uncontrolled private-sector cost escalation are coll...