MDD treatment modeling demonstrates that sequenced interventions for major depressive disorder consistently deliver superior quality-adjusted life years and net monetary benefits compared with no active treatment. All examined pathways outperformed inaction, with an SSRI-first sequence followed b...

Levacetylleucine A-T treatment has delivered compelling Phase III results, producing statistically significant and clinically meaningful improvements in ataxia severity and daily function for both pediatric and adult patients with ataxia-telangiectasia (A-T). The

The Insulin Cost Policy Impact became clear in 2023 after the Inflation Reduction Act limited out-of-pocket insulin expenses to $35 per 30-day supply for Medicare Part D beneficiaries. According to a JAMA Network study, the c...

Parkinson's Cognitive Measurement has emerged as the decisive constraint on our ability to forecast cognitive decline in Parkinson disease. A major new analysis shows that even the most advanced machine learning models deliver only chance-level accuracy when predicting individual cognitive trajec...

The mifepristone safety study launched by the FDA in April 2026 is actively collecting high-quality real-world data to determine whether the current Risk Evaluation and Mitigation Strategy (REMS) program still strikes the right balance between clinical benefits and potential harms. S...

HIV prevention access strategies have reached a pivotal moment in South Africa with the imminent launch of lenacapavir, a long-acting injectable administered twice yearly. This coordinated effort directly confronts the country’s immense HIV burden, including 7.8 million people living with the vir...