Biologic Dispensing Implementation Gaps Challenge Patient Access to Care
Biologic Dispensing Implementation Gaps Challenge Patient Access to Care

By João L. Carapinha

July 7, 2026

Biologic dispensing implementation gaps are undermining equitable access to advanced therapies for inflammatory bowel disease across Portugal’s public hospitals. Despite clear legislative changes, institutions continue to reject prescriptions for biologics written by private specialists, forcing ...
Curative Therapy Commercialization Gap and Global Access Challenges
Curative Therapy Commercialization Gap and Global Access Challenges
The curative therapy commercialization gap remains one of healthcare’s most stubborn contradictions: cell and gene therapies can deliver complete disease resolution, yet structural, financial, and infrastructural barriers keep them from reaching most patients who need them. This disconnect is esp...
Transatlantic Reference Pricing Innovation and Its Impact on Global Pharmaceutical Dynamics
Transatlantic Reference Pricing Innovation and Its Impact on Global Pharmaceutical Dynamics
The transatlantic reference pricing innovation is fundamentally altering pharmaceutical revenue expectations and patient access on both sides of the Atlantic. By anchoring U.S. reimbursement to the second-lowest net price among a basket of wealthy nations, the Most Favored Nation (MFN) policy cre...
Impact of Practice-Level Telehealth on Quality Outcomes in Chronic Care
Impact of Practice-Level Telehealth on Quality Outcomes in Chronic Care

By João L. Carapinha

July 6, 2026

Practice-level telehealth quality outcomes remained stable for access and preventable hospitalizations among Medicare beneficiaries with chronic conditions during the COVID-19 pandemic. High-adopting primary care practices preserved care continuity while delivering modestly lower performance on s...
Large Language Models in Evidence-Based Medicine
Large Language Models in Evidence-Based Medicine

By João L. Carapinha

July 3, 2026

Large language models deliver rapid synthesis of medical literature, but according to research on fast information and slow evidence, they cannot independently generate validated evidence for clinical decisions. These tools sit at a...
African Pharmacogenomic Integration Enhancing Essential Medicine Prescribing in Africa
African Pharmacogenomic Integration Enhancing Essential Medicine Prescribing in Africa
African Pharmacogenomic Integration has become an urgent policy priority, with evidence showing that more than 10 percent of essential medicines across Africa require genetically guided prescribing to prevent harm and improve outcomes in diverse populations. Current dosage guidelines for HIV, ...
Search By Category
Curative Therapy Commercialization Gap and Global Access Challenges

Global Updates

Curative Therapy Commercialization Gap and Global Access Challenges

By João L. Carapinha

July 7, 2026

The curative therapy commercialization gap remains one of healthcare’s most stubborn contradictions: cell and gene therapies can deliver complete disease resolution, yet structural, financial, and infrastructural barriers keep them from reaching most patients who need them. This disconnect is esp...
Impact of Practice-Level Telehealth on Quality Outcomes in Chronic Care

Global Updates

Impact of Practice-Level Telehealth on Quality Outcomes in Chronic Care

By João L. Carapinha

July 6, 2026

Practice-level telehealth quality outcomes remained stable for access and preventable hospitalizations among Medicare beneficiaries with chronic conditions during the COVID-19 pandemic. High-adopting primary care practices preserved care continuity while delivering modestly lower performance on s...
Large Language Models in Evidence-Based Medicine

Global Updates

Large Language Models in Evidence-Based Medicine

By João L. Carapinha

July 3, 2026

Large language models deliver rapid synthesis of medical literature, but according to research on fast information and slow evidence, they cannot independently generate validated evidence for clinical decisions. These tools sit at a...
Retracted Trial Publication Undermines Support for Avacopan in AAV Treatment

Global Updates

Retracted Trial Publication Undermines Support for Avacopan in AAV Treatment

By João L. Carapinha

July 1, 2026

The Retracted Trial Publication of the ADVOCATE study has eliminated the central evidence that supported approval of Tavneos (avacopan) for severe active anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV). At the request of two lead academic authors, the

Upcoming Global Events

Upcoming Events:
August 29-September 2, 2026 42nd Annual ISPE Meeting | Milan, Italy Website →
September 3-4, 2026 13th RWE, Market Access, Pricing & Reimbursement 2026 Europe | Hilton London Kensington, London, UK Website →
September 6-8, 2026 ISPOR Asia Pacific Summit 2026 | Bangkok, Thailand Website →